AMLOPIDINE BEZYLATE TABLETS WITH IMPROVED STABILITY
摘要
The invention relates to amlodipine bezylate tablets with improved stability of the active ingredient and reduced in weight containing microcrystalline cellulose, a lubricant and a disintegrating agent. Said tablets comprise 4-6 % by weight of amlodipine bezylate as active ingredient together with 87 to 94 % by weight of microcrystalline cellulose, 1-5 % by weight of a disintegrating agent, 0.5 to 1.5 % by weight of a lubricant and 0.2 to 1.0 % by weight of colloidal silicon dioxide. The invention also relates to a process for the preparation of the said tablets.
申请公布号
EP1458384(A1)
申请公布日期
2004.09.22
申请号
EP20020788262
申请日期
2002.12.17
申请人
EGIS GYOGYSZERGYAR RT.
发明人
FEKETE, PAL;KIRALYNE IGNACZ, MARIA;TOEMPE, PETER;GORA, LASZLONE;SZENTGROTI, PALNE;LEVENTISZNE HUSZAR, MAGDOLNA;THUROCZI, PALNE;LONKAINE MAGYAR, OLGA