发明名称 |
Influenza M2 protein mutant viruses as live influenza attenuated vaccines |
摘要 |
A method to prepare recombinant influenza viruses comprising a mutant M2 protein which has a deletion of two or more residues in the cytoplasmic tail and is attenuated in vivo, is provided, as well the resulting virus and vaccines with the virus. |
申请公布号 |
US2009074812(A1) |
申请公布日期 |
2009.03.19 |
申请号 |
US20080214414 |
申请日期 |
2008.06.18 |
申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
WATANABE TOKIKO;KAWAOKA YOSHIHIRO |
分类号 |
A61K39/285;C12N7/01 |
主分类号 |
A61K39/285 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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