发明名称 SUBSTITUTED 4-PHENYL PYRIDINES FOR TREATING NK-1 RECEPTOR ASSOCIATED DISEASES
摘要 PROBLEM TO BE SOLVED: To provide: new derivatives of 4-phenyl-pyridine compounds that are effective NKreceptor antagonists, with enhanced physicochemical and/or biological properties; and methods for producing the same.SOLUTION: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the neurokinin (NKj) receptor, including compounds represented by the formula in the figure.SELECTED DRAWING: None
申请公布号 JP2016147868(A) 申请公布日期 2016.08.18
申请号 JP20160034427 申请日期 2016.02.25
申请人 HELSINN HEALTHCARE SA 发明人 LUCA FADINI;PETER MANINI;CLAUDIO PIETRA;CLAUDIO GIULIANO;EMANUELA LOVATI;CANNELLA ROBERTA;ALESSIO VENTURINI;VALENTINO J STELLA
分类号 C07D213/75;A61K31/4178;A61K31/439;A61K31/46;A61K31/473;A61K31/496;A61K31/573;A61K31/675;A61K45/00;A61P1/08;A61P13/10;A61P25/22;A61P25/24;A61P43/00;C07D213/89;C07F9/09;C07F9/6509 主分类号 C07D213/75
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