发明名称 |
SUBSTITUTED 4-PHENYL PYRIDINES FOR TREATING NK-1 RECEPTOR ASSOCIATED DISEASES |
摘要 |
PROBLEM TO BE SOLVED: To provide: new derivatives of 4-phenyl-pyridine compounds that are effective NKreceptor antagonists, with enhanced physicochemical and/or biological properties; and methods for producing the same.SOLUTION: Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the neurokinin (NKj) receptor, including compounds represented by the formula in the figure.SELECTED DRAWING: None |
申请公布号 |
JP2016147868(A) |
申请公布日期 |
2016.08.18 |
申请号 |
JP20160034427 |
申请日期 |
2016.02.25 |
申请人 |
HELSINN HEALTHCARE SA |
发明人 |
LUCA FADINI;PETER MANINI;CLAUDIO PIETRA;CLAUDIO GIULIANO;EMANUELA LOVATI;CANNELLA ROBERTA;ALESSIO VENTURINI;VALENTINO J STELLA |
分类号 |
C07D213/75;A61K31/4178;A61K31/439;A61K31/46;A61K31/473;A61K31/496;A61K31/573;A61K31/675;A61K45/00;A61P1/08;A61P13/10;A61P25/22;A61P25/24;A61P43/00;C07D213/89;C07F9/09;C07F9/6509 |
主分类号 |
C07D213/75 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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