| 发明名称 |
ANTIBODY DRUG CONJUGATE, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USES THEREOF |
| 摘要 |
Disclosed are an antibody drug conjugate IB, which uses ether linkages for connection, and improves the water solubility, stability and cytotoxicity in vivo and in vitro, and an intermediate, a pharmaceutical composition, and uses of the antibody drug conjugate. The antibody drug conjugate has simple synthetic steps and a high yield. |
| 申请公布号 |
WO2016197946(A1) |
申请公布日期 |
2016.12.15 |
| 申请号 |
WO2016CN85275 |
申请日期 |
2016.06.08 |
| 申请人 |
XDCEXPLORER (SHANGHAI) CO., LTD. |
发明人 |
XIANG, Shaoyun;LIU, Shifeng;YANG, Hongyu;MA, Xingquan |
| 分类号 |
A61K47/48;A61K31/537;A61K39/395;A61P35/00 |
主分类号 |
A61K47/48 |
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