Use of active antithrombin III having endothelial cell proliferation inhibitory activity for combating diseases associated with angiogenesis, e.g. retinopathy, neuropathy, leprosy and cancer

摘要

Active antithrombin III (I), showing thrombin inhibitory activity and affinity for heparin, is used in the prophylaxis and treatment of diseases caused or induced by angiogenesis or arteriogenesis.