| 发明名称 |
ADDUCT OF 5-FLUOROURACIL AND SODIUM SALT OF DIPHENYL PHOSPHORoUS ACID FOR THE TREATMENT OF ONCOLOGICAL DISEASES |
| 摘要 |
The invention relates to medicine, namely to the oncopharmacology.It has been established for the first time that adduct of 5-fluorouracil and sodium salt of diphenyl phosphorous acid has an evident antitumor activity on models of experimental tumor growth, exceeding similar one of the preparation-standard of 5-fluorouracil. The mentioned adduct can be used for the treatment of tumor diseases of man. |
| 申请公布号 |
UA89504(C2) |
申请公布日期 |
2010.02.10 |
| 申请号 |
UA20070003652 |
申请日期 |
2007.04.03 |
| 申请人 |
INSTITUTE OF PHARMACOLOGY AND TOXYCOLOGY OF AMS OF UKRAINE |
发明人 |
STEFANOV OLEKSANDR VIKTOROVYCH;SHARYKINA NADIA IVANIVNA;DEMCHENKO ANATOLII MYKHAILOVYCH;KUDRIAVTSEVA IRYNA HEORHIIVNA;KHAVYCH OLHA OLEKSANDRIVNA;TYTARENKO IVAN PETROVYCH;BOBKOVA LIUDMYLA STANISLAVIVNA;SERHIEIEV VALENTYN SERHIIOVYCH;HOLUBOV MYKHAILO IVANOVYCH;SERHIIENKO OLHA VOLODYMYRIVNA |
| 分类号 |
A61K31/52;A61K31/755;C07D473/04 |
主分类号 |
A61K31/52 |
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