发明名称 RETINOL-MODIFIED COLLAGEN, METHOD FOR PRODUCING SAME, AND EXTERNAL COMPOSITION FOR SKIN CONTAINING SAME
摘要 PROBLEM TO BE SOLVED: To provide a compound which exhibits a higher effect of preventing wrinkle formation, a higher effect of improving wrinkles, a higher effect of making the skin beautiful, and a higher effect of improving skin quality than conventional retinol and retinol derivatives in a sustained manner, and a method for producing the same, and an external composition for the skin and a sheet-shaped cosmetic each containing the same as an active ingredient.SOLUTION: Disclosed are retinol-modified collagen in which a dicarboxylic acid is attached to at least one hydroxyl group of collagen and retinol is attached to a carboxyl group of at least one attached dicarboxylic acid, a method for producing the same, and an external composition for the skin and a sheet-shaped cosmetic each containing the same as an active ingredient.SELECTED DRAWING: None
申请公布号 JP2016104804(A) 申请公布日期 2016.06.09
申请号 JP20160027920 申请日期 2016.02.17
申请人 NARA INSTITUTE OF SCHIENCE AND TECHNOLOGY;SUNSTAR INC 发明人 TANIHARA MASAO;TAKAICHI KANA;MAEDA MARIKO;MITSUI TSUKASA;YAMAMOTO KAZUJI;HIRANO AKIKO
分类号 C07K19/00;A61K8/02;A61K8/65;A61K8/67;A61K31/07;A61K38/17;A61K47/14;A61K47/48;A61P17/00;A61P43/00;A61Q19/08;C07K14/78;C12N15/09 主分类号 C07K19/00
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