发明名称 |
RETINOL-MODIFIED COLLAGEN, METHOD FOR PRODUCING SAME, AND EXTERNAL COMPOSITION FOR SKIN CONTAINING SAME |
摘要 |
PROBLEM TO BE SOLVED: To provide a compound which exhibits a higher effect of preventing wrinkle formation, a higher effect of improving wrinkles, a higher effect of making the skin beautiful, and a higher effect of improving skin quality than conventional retinol and retinol derivatives in a sustained manner, and a method for producing the same, and an external composition for the skin and a sheet-shaped cosmetic each containing the same as an active ingredient.SOLUTION: Disclosed are retinol-modified collagen in which a dicarboxylic acid is attached to at least one hydroxyl group of collagen and retinol is attached to a carboxyl group of at least one attached dicarboxylic acid, a method for producing the same, and an external composition for the skin and a sheet-shaped cosmetic each containing the same as an active ingredient.SELECTED DRAWING: None |
申请公布号 |
JP2016104804(A) |
申请公布日期 |
2016.06.09 |
申请号 |
JP20160027920 |
申请日期 |
2016.02.17 |
申请人 |
NARA INSTITUTE OF SCHIENCE AND TECHNOLOGY;SUNSTAR INC |
发明人 |
TANIHARA MASAO;TAKAICHI KANA;MAEDA MARIKO;MITSUI TSUKASA;YAMAMOTO KAZUJI;HIRANO AKIKO |
分类号 |
C07K19/00;A61K8/02;A61K8/65;A61K8/67;A61K31/07;A61K38/17;A61K47/14;A61K47/48;A61P17/00;A61P43/00;A61Q19/08;C07K14/78;C12N15/09 |
主分类号 |
C07K19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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