| 发明名称 |
Engineered CRISPR-CAS9 Nucleases with Altered PAM Specificity |
| 摘要 |
Engineered CRISPR-Cas9 nucleases with altered and improved PAM specificities and their use in genomic engineering, epigenomic engineering, and genome targeting. |
| 申请公布号 |
US2016312199(A1) |
申请公布日期 |
2016.10.27 |
| 申请号 |
US201615208461 |
申请日期 |
2016.07.12 |
| 申请人 |
The General Hospital Corporation |
发明人 |
Joung J. Keith;Kleinstiver Benjamin |
| 分类号 |
C12N9/22;C12N15/10 |
主分类号 |
C12N9/22 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An isolated Staphylococcus aureus Cas9 (SaCas9) protein with mutations at one or more of the following positions: E782, N968, and/or R1015. |
| 地址 |
Boston MA US |
