METHODS AND COMPOSITIONS FOR INDUCING BONE SYNTHESIS
摘要
<p>The present invention is based on the discovery that overexpression of OSM leads to bone formation and that OSM expression inhibits adipogenesis. The present invention provides methods that modulate bone formation and adipogenesis. The invention also provides compositions that modulate bone formation. The compositions comprise OSM or a nucleic acid encoding OSM and an anti-inflammatory agent.</p>
申请公布号
WO2007140590(A1)
申请公布日期
2007.12.13
申请号
WO2007CA00981
申请日期
2007.06.01
申请人
MCMASTER UNIVERSITY;RICHARDS, CARL;BEITZ, JACLYN;KERR, CHRISTINE;LANGDON, CARRIE;SMYTH, DAVID
发明人
RICHARDS, CARL;BEITZ, JACLYN;KERR, CHRISTINE;LANGDON, CARRIE;SMYTH, DAVID