发明名称 |
METHOD FOR TREATMENT OF PROSTATE CANCER AND SCREENING OF PATIENTS BENEFITING FROM SAID METHOD |
摘要 |
The invention relates to a method for treating ERG-positive prostate cancer patients with an agent counteracting one or more ERG-associated genes and/or manipulating of one or more ERG-related pathways, optionally in combination with an androgen deprivation therapy. Furthermore, the invention concerns methods for screening prostate cancer patients which may benefit from said treatment, assessing the efficacy of a therapy for treating prostate cancer in a patient, assessing progression of prostate cancer in a patient, selecting an agent to be tested for usefulness in the treatment of prostate cancer, and for assessing prostate carcinogenic potential of an agent. |
申请公布号 |
WO2008023087(A2) |
申请公布日期 |
2008.02.28 |
申请号 |
WO2007FI00204 |
申请日期 |
2007.08.20 |
申请人 |
VALTION TEKNILLINEN TUTKIMUSKESKUS;ILJIN, KRISTIINA;NEES, MATTHIAS;KALLIONIEMI, OLLI;BJOERKMAN, MARI |
发明人 |
ILJIN, KRISTIINA;NEES, MATTHIAS;KALLIONIEMI, OLLI;BJOERKMAN, MARI |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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