发明名称 Bicyclic-fused heteroaryl or aryl compounds and their use as IRAK4 inhibitors
摘要 Compounds, tautomers and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula Ia, as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
申请公布号 AU2015242291(A1) 申请公布日期 2016.10.13
申请号 AU20150242291 申请日期 2015.03.26
申请人 Pfizer Inc. 发明人 Anderson, David Randolph;Bunnage, Mark Edward;Curran, Kevin Joseph;Dehnhardt, Christoph Martin;Gavrin, Lori Krim;Goldberg, Joel Adam;Han, Seungil;Hepworth, David;Huang, Horng-Chih;Lee, Arthur;Lee, Katherine Lin;Lovering, Frank Eldridge;Lowe, Michael Dennis;Mathias, John Paul;Papaioannou, Nikolaos;Patny, Akshay;Pierce, Betsy Susan;Saiah, Eddine;Strohbach, Joseph Walter;Trzupek, John David;Vargas, Richard;Wang, Xiaolun;Wright, Stephen Wayne;Zapf, Christoph Wolfgang
分类号 C07D207/26;A61K31/47;A61K31/4709;A61K31/472;A61K31/4725;A61K31/517;A61P11/06;A61P13/12;A61P17/06;A61P19/02;A61P29/00;C07C69/94;C07C235/66;C07D207/273;C07D209/52;C07D215/48;C07D217/02;C07D217/22;C07D217/24;C07D239/86;C07D239/88;C07D263/24;C07D401/12;C07D401/14;C07D403/12;C07D405/12;C07D405/14;C07D413/12;C07D417/12;C07D487/04;C07D491/056;C07D498/04;C07F7/18 主分类号 C07D207/26
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