| 发明名称 |
FORMULATIONS FOR VIROSOMES |
| 摘要 |
This disclosure provides virosome formulations, in particular, liquid pharmaceutical formulations comprising virosomes. |
| 申请公布号 |
US2016317646(A1) |
申请公布日期 |
2016.11.03 |
| 申请号 |
US201415106234 |
申请日期 |
2014.12.18 |
| 申请人 |
CRUCELL HOLLAND B.V |
发明人 |
Adriaansen Janik;Doro Francesco |
| 分类号 |
A61K39/145;A61K47/26;A61K9/51;A61K47/02 |
主分类号 |
A61K39/145 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A liquid composition comprising:
a) virosomes; b) a KH2PO4/Na2HPO4 buffer, wherein the phosphate concentration is between 15 mM and 30 mM; c) a salt, wherein the salt concentration is higher than 60 mM; and d) trehalose, wherein the trehalose concentration is between 2% (w/w) and 10% (w/w), wherein said composition has a pH between 6.5 and 8. |
| 地址 |
Leiden NL |
