发明名称 |
BIOMARKERS ASSOCIATED WITH LSD1 INHIBITORS AND USES THEREOF |
摘要 |
Therapy employing LSDl inhibitors, in particular arylcyclopropylamino compounds, and uses thereof to assess target engagement and to follow patient response to treatment, in particular by measuring the expression of the genes S100A8 and S100A9 and in particular in the context of CNS diseases, e.g. Alzheimer's disease, or multiple sclerosis. |
申请公布号 |
WO2016198649(A1) |
申请公布日期 |
2016.12.15 |
申请号 |
WO2016EP63368 |
申请日期 |
2016.06.10 |
申请人 |
ORYZON GENOMICS, S.A. |
发明人 |
MAES, Tamara;MASCARÓ CRUSAT, Cristina;ROTLLANT POZO, David |
分类号 |
C12Q1/68;A61K31/42;G01N33/50 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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