| 主权项 |
1. A method for the treatment of residual symptoms, comprising administering to a patient in need thereof an effective amount of a compound of Formula I:wherein:
X is —O—, —NH— or —N(CH3)—; Y is —O—, —C(R2)(OH)—, —C(R3)(OR1) or —C(O)—; and R1 is —C1-6 alkyl (e.g., methyl) or —C(O)—C1-21 alkyl (e.g., —C(O)—C1-5alkyl, —C(O)—C6-15alkyl or —C(O)—C16-21alkyl), preferably said alkyl is a straight chain, optionally saturated or unsaturated and optionally substituted with one or more hydroxy or C1-22alkoxy (e.g., ethoxy) groups, for example R1 is —C(O)—C6alkyl, —C(O)—C7alkyl, —C(O)—C9alkyl, —C(O)—C11alkyl, —C(O)—C13alkyl or —C(O)—C15alkyl wherein such compound hydrolyzes to form the residue of a natural or unnatural, saturated or unsaturated fatty acid, e.g., the compound hydrolyzes to form the hydroxy compound on the one hand and octanoic acid, decanoic acid, dodecanoic acid, tetradecanoic acid or hexadecanoic acid on the other hand); R2 is H or —C1-6alkyl (e.g., methyl); and R3 is H or —C1-6 alkyl (e.g., methyl);in free or pharmaceutically acceptable salt form. |
