发明名称 |
SODIUM SALT OF URIC ACID TRANSPORTER INHIBITOR AND CRYSTALLINE FORM THEREOF |
摘要 |
The present invention relates to a sodium salt of a uric acid transporter inhibitor and the crystalline form thereof. In particular, the present invention relates to the sodium salt of a uric acid transporter (URAT1) inhibitor, and the I-type crystal and the preparation method thereof. The present invention relates to 1-((6-bromo-quinoline-4-yl)thio)cyclobutyl sodium formate (the compound of formula (I)), and the I-type crystal and the preparation method thereof. The I-type crystal of the compound of formula (I) obtained in the present invention has a good crystal form stability and chemical stability, and the crystallization solvent used has a low toxicity and low residue, and can be better used in clinical treatment. |
申请公布号 |
WO2016188444(A1) |
申请公布日期 |
2016.12.01 |
申请号 |
WO2016CN83423 |
申请日期 |
2016.05.26 |
申请人 |
JIANGSU HENGRUI MEDICINE CO., LTD. |
发明人 |
WU, Guaili;QIU, Zhenjun;SU, Yunpeng;LU, Xi |
分类号 |
C07D215/36;A61K31/47;A61P19/06 |
主分类号 |
C07D215/36 |
代理机构 |
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代理人 |
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地址 |
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