发明名称 SODIUM SALT OF URIC ACID TRANSPORTER INHIBITOR AND CRYSTALLINE FORM THEREOF
摘要 The present invention relates to a sodium salt of a uric acid transporter inhibitor and the crystalline form thereof. In particular, the present invention relates to the sodium salt of a uric acid transporter (URAT1) inhibitor, and the I-type crystal and the preparation method thereof. The present invention relates to 1-((6-bromo-quinoline-4-yl)thio)cyclobutyl sodium formate (the compound of formula (I)), and the I-type crystal and the preparation method thereof. The I-type crystal of the compound of formula (I) obtained in the present invention has a good crystal form stability and chemical stability, and the crystallization solvent used has a low toxicity and low residue, and can be better used in clinical treatment.
申请公布号 WO2016188444(A1) 申请公布日期 2016.12.01
申请号 WO2016CN83423 申请日期 2016.05.26
申请人 JIANGSU HENGRUI MEDICINE CO., LTD. 发明人 WU, Guaili;QIU, Zhenjun;SU, Yunpeng;LU, Xi
分类号 C07D215/36;A61K31/47;A61P19/06 主分类号 C07D215/36
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