| 发明名称 |
4-(7-HALO-2-QUINO (XA-) LINYLOXY) PHENOXY-PROPIONIC ACID DERIVATIVES AS ANTINEOPLASTIC AGENTS |
| 摘要 |
The invention provides compounds of the formula (I): wherein A, X, Y, and Z are as defined in the specification. The compounds are effective anti-tumor agents. The invention also provides pharmaceutical compositions comprising a compound of the above formula or a salt thereof, intermediates useful for preparing a compound of the above formula, and therapeutic methods comprising administering a compound of the above formula or a salt thereof to a mammal in need thereof. |
| 申请公布号 |
EA009679(B1) |
申请公布日期 |
2008.02.28 |
| 申请号 |
EA20050000095 |
申请日期 |
2003.07.03 |
| 申请人 |
WAYNE STATE UNIVERSITY |
发明人 |
HORWITZ JEROME, P.;CORBETT THOMAS, H.;PALOMINO EDUARDO;POLIN LISA;HAZELDINE STUART, T. |
| 分类号 |
C07D215/22;A01N43/42;A01N43/60;A61K31/47;A61K31/498;A61P35/00;A61P35/02;A61P43/00;C07D215/227;C07D215/60;C07D241/36;C07D241/44 |
主分类号 |
C07D215/22 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
