发明名称 |
Fused imidazole derivatives useful as IDO inhibitors |
摘要 |
FUSED IMIDAZOLE DERIVATIVES USEFUL AS IDO INHIBITORS Presently provided are IDO inhibitors and pharmaceutical compositions thereof, useful for modulating an activity of indoleamine 2,3-dioxygenase; treating indoleamine 2,3-dioxygenase (IDO) mediated immunosuppression; treating a medical conditions that benefit from the inhibition of enzymatic activity of indoleamine-2,3-dioxygenase; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; treating tumor-specific immunosuppression associated with cancer; and treating immunosuppression associated with an infectious disease. |
申请公布号 |
AU2014274564(B2) |
申请公布日期 |
2016.10.06 |
申请号 |
AU20140274564 |
申请日期 |
2014.12.10 |
申请人 |
NewLink Genetics Corporation |
发明人 |
Mautino, Mario;Kumar, Sanjeev;Waldo, Jesse;Jaipuri, Firoz;Kesharwarni, Tanay;Zhang, Xiaoxia |
分类号 |
C07D487/04;A61K31/4188;A61P37/02 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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