发明名称 Fused imidazole derivatives useful as IDO inhibitors
摘要 FUSED IMIDAZOLE DERIVATIVES USEFUL AS IDO INHIBITORS Presently provided are IDO inhibitors and pharmaceutical compositions thereof, useful for modulating an activity of indoleamine 2,3-dioxygenase; treating indoleamine 2,3-dioxygenase (IDO) mediated immunosuppression; treating a medical conditions that benefit from the inhibition of enzymatic activity of indoleamine-2,3-dioxygenase; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; treating tumor-specific immunosuppression associated with cancer; and treating immunosuppression associated with an infectious disease.
申请公布号 AU2014274564(B2) 申请公布日期 2016.10.06
申请号 AU20140274564 申请日期 2014.12.10
申请人 NewLink Genetics Corporation 发明人 Mautino, Mario;Kumar, Sanjeev;Waldo, Jesse;Jaipuri, Firoz;Kesharwarni, Tanay;Zhang, Xiaoxia
分类号 C07D487/04;A61K31/4188;A61P37/02 主分类号 C07D487/04
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