TETRAPEPTIDE STIMULATING THE RETINAL FUNCTION AND THE METHOD OF ITS APPLICATION

摘要

The invention relates to medicine and concerns the ophthalmologic application of synthetic tetrapeptide Ala-Glu-Asp-Gly in the treatment for eye diseases and pathologic states by means of stimulating the retinal functions. The pharmaceutical peptide substance is proposed to treat for diseases and pathologic states accompanied by disturbed retinal functions and containing a pharmaceutically admissible carrier and a therapeutically effective quantity of tetrapeptide alanyl-glutamyl-asparagyl-glycine or one of its pharmaceutically admissible salts of the amino acid group (acetate, hydrochloride or oxalate) or of carboxyl groups (salts of metals - sodium, potassium, calcium, lithium, zinc, magnesium, as well as of organic and inorganic cations - ammonium and triethylammonium). There is claimed a method of treating for diseases and pathologic states embracing a preventive or therapeutic administration to a patient of the proposed pharmaceutical peptide substance parenterally: parabulbarly and/or intramuscularly in the doses of 0.1-10 mu m/kg of the body weight at least once a day for a period necessary to attain a therapeutic effect depending on the character and severity of the pathologic process.