ENTECAVIR-CONTAINING TABLET, PRODUCTION METHOD THEREOF, AND ORALLY DISINTEGRATING TABLET USING THE SAME

摘要

PROBLEM TO BE SOLVED: To provide entecavir-containing tablets in which the production of entecavir analogues is inhibited.SOLUTION: According to one aspect of the present invention, an entecavir-containing tablet characterized by consisting of a pharmaceutical composition containing entecavir, sugar alcohol, and a binder selected from hydroxypropylcellulose, hypromellose, and povidone is provided. In one embodiment, the sugar alcohol is D-mannitol. In one embodiment, the binder is hydroxypropylcellulose.SELECTED DRAWING: Figure 1