发明名称 |
HIGHLY WATER-SOLUBLE SALTS OF A SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKER AND USES THEREOF |
摘要 |
The present invention includes surprisingly water-soluble salts of a phenylalkylamine compound that are potent antagonists of L-type calcium channels. Aqueous solutions including salts of the instant invention are formulated for nasal administration and provide a novel therapeutic platform for the treatment of stable angina, migraine, and cardiac arrhythmia, such as paroxysmal supraventricular tachycardia. |
申请公布号 |
WO2016165014(A1) |
申请公布日期 |
2016.10.20 |
申请号 |
WO2016CA50425 |
申请日期 |
2016.04.13 |
申请人 |
MILESTONE PHARMACEUTICALS INC. |
发明人 |
MARTIN P., Maguire |
分类号 |
A61K31/277;A61K9/08;A61K31/185;A61P9/00;A61P9/06;A61P9/10;A61P25/06;C07C255/37 |
主分类号 |
A61K31/277 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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