发明名称 Antiinflammatory and antitumor 2-oxothiazoles and 2-oxothiophenes compounds
摘要 Abstract x S (R1 )n R4 A compound of formula (I) R2 (I) wherein X is 0, C=O or S; Y is N or CH; R2 and R4 are each independently H, -(CH 2)pCOOH, -(CH 2)pCON(R 5)2 or -(CH 2)pCOOCi-6alkyl; or R 2 and R4 together form a 6-membered phenyl ring fused to the five membered ring; each R1 is independently selected from H, halo (e.g. fluoro or chloro), C6-1oaryl, C7-12arylalkyl, C2-12 alkenyl; OCl-12 alkyl, OC2-12 alkenyl or a Ci-12 alkyl group; each R5 is H or Ci-6 alkyl; each p is 0 to 3; n is 1 to 4; or a salt, ester, solvate, N-oxide, or prodrug thereof, e.g. a salt thereof. R461R71 1 (GHMattr) P100447 Al J
申请公布号 AU2016266022(A1) 申请公布日期 2016.12.15
申请号 AU20160266022 申请日期 2016.11.30
申请人 AVEXXIN AS 发明人 JOHANSEN, Berit;SANDBERG, Marcel;AUKRUST, Inger-Reidun;KOKOTOS, George;BARBAYIANNI, Efrosini
分类号 C07D277/24;A61K31/426;A61P1/00;C07D277/56 主分类号 C07D277/24
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