Methods of Isolating Extracellular Vesicles

摘要

The specification provides methods for isolating extracellular vesicles. Extracellular vesicles can be efficiently isolated, e.g., from biological fluids or cell culture media, using a heparin-coated solid support.

主权项

1. A method of isolating an extracellular vesicle (EV), the method comprising:
providing a sample comprising an EV; contacting the sample with a heparin-coated solid support under conditions that allow the solid support to bind to the EV; and separating the solid support-bound EV from the sample, thereby isolating the EV from the sample.