PRODUCTION METHOD OF OLMESARTAN MEDOXOMIL

摘要

PROBLEM TO BE SOLVED: To provide a method for simply producing a crystal of high purity olmesartan medoxomil from a crude body of olmesartan medoxomil including 4-(2-hydroxypropane-2-yl)-2- propyl-1-{[2'-(1H-tetrazole-5-yl)biphenyl-4-yl] methyl}-1H-imidazole-5-carboxylic acid as a contaminant.SOLUTION: A crude body of olmesartan medoxomil including 4-(2-hydroxypropane-2-yl)-2-propyl-1-{[2'-(1H- tetrazole-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid as a contaminant is treated by a specific absorbent using a mixed solvent of acetone and water, and thereby high purity olmesartan medoxomil is simply produced.