MODIFIED PROTEINS WHICH BIND EXTRACELLULAR MATRIX COMPONENTS
摘要
A viral or non-viral vector particle having a modified viral surface protein wherein the viral surface protein is modified to include a targeting polypeptide including a binding region which binds to an extracellular matrix component. Such vector particles are useful in delivering genes encoding therapeutic agents to cells located at the site of an exposed extracellular matrix component.
申请公布号
WO9844938(A1)
申请公布日期
1998.10.15
申请号
WO1998US06936
申请日期
1998.04.08
申请人
UNIVERSITY OF SOUTHERN CALIFORNIA;HALL, FREDERICK, L.;GORDON, ERLINDA, MARIA;ANDERSON, W., FRENCH;STARNES, VAUGHN, A.
发明人
HALL, FREDERICK, L.;GORDON, ERLINDA, MARIA;ANDERSON, W., FRENCH;STARNES, VAUGHN, A.