发明名称 |
A PROCESS FOR THE PRODUCTION OF OF 19-NORPREGN-4-EN-3,20-DIONE-17.ALPHA.-OL (GESTONORONE) AND INTERMEDIATES THEREFOR |
摘要 |
The present invention relates to a new stereoselective process for the synthesis of 17(α)-17-acetyl-17-hydroxy-estr-4-en-3-one of formula (I), as well as to the new intermediates of the process. The 17(α)-17-acetyl-17-hy droxy-estr-4-en-3 -one (gestonorone) is an important intermediate in the synthesis of the active ingredients having progestogen activity - such as gestonorone capronate and nomegestroi acetate. Formulas (I), (II) and (III). |
申请公布号 |
EP3083655(A1) |
申请公布日期 |
2016.10.26 |
申请号 |
EP20140833541 |
申请日期 |
2014.12.15 |
申请人 |
RICHTER GEDEON NYRT. |
发明人 |
CSÖRGEI, JÁNOS;HORVÁTH, ANITA;SÁNTA, CSABA;MAHÓ, SÁNDOR;BÉNI, ZOLTÁN;HORVÁTH, JÁNOS |
分类号 |
C07J1/00;C07J7/00;C07J41/00;C07J51/00 |
主分类号 |
C07J1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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