TREATMENT OF BETA-THALASSEMIA USING ACTRII LIGAND TRAPS
摘要
Provided herein are methods of treating beta-thalassemia by subcutaneous administration of about 0.8 mg/kg of an ActRII signaling inhibitor. Also provided herein are methods of adjusting the dose of the ActRII signaling inhibitor administered to the subject.
申请公布号
WO2016183280(A1)
申请公布日期
2016.11.17
申请号
WO2016US31999
申请日期
2016.05.12
申请人
CELGENE CORPORATION;ACCELERON PHARMA INC.
发明人
ATTIE, Kenneth, M.;LAADEM, Abderrahmane;CHOPRA, Rajesh;BACKSTROM, Jay