| 发明名称 |
ANTIBODIES AGAINST MONOCYTE CHEMOTACTIC PROTEINS |
| 摘要 |
The invention provides antibodies that bind to a plurality of β-chemokines, particularly monocyte chemotactic proteins MCP-1, MCP-2 and MCP-3. The invention also provides cells producing the antibodies, and methods of making and using the same. |
| 申请公布号 |
US2016185846(A1) |
申请公布日期 |
2016.06.30 |
| 申请号 |
US201514746555 |
申请日期 |
2015.06.22 |
| 申请人 |
BIOGEN MA INC. |
发明人 |
DE FOUGEROLLES Antonin R.;KOTELIANSKI Victor E.;REID Carl;GARBER Ellen |
| 分类号 |
C07K16/24 |
主分类号 |
C07K16/24 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A monoclonal antibody or antigen-binding fragment thereof comprising a heavy chain variable region having a CDR1 domain comprising the sequence set forth in SEQ ID NO:13, a CDR2 domain comprising the sequence set forth in SEQ ID NO:14, and a CDR3 domain comprising the sequence set forth in SEQ ID NO:15. |
| 地址 |
Cambridge MA US |
