发明名称 DIAGNOSTIC TECHNIQUE FOR PREMATURE DETACHMENT OF NORMALLY LOCATED PLACENTA
摘要 FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to pathologic anatomy, and concerns diagnosing premature detachment of normally located placenta (PDNLP), caused by inflammation. Method is implemented by morphological study of basal decidual shell with immunohistochemical staining method of determining specific area of placenta basal plate per fibronectin-positive structure, which is calculated by formulawhereis number of points in grid per fibronectin-positive structure; A - total number of points in grid (100). CD68 macrophages molecules expression index molecules is determined. If specific area of placenta basal plate per fibronectin is equal to 20 % or less, and CD68 macrophages molecules expression index molecules is equal to 2.90 s.u. or more, placenta detachment is diagnosed. Use of invention provides extending range of morphological diagnostic agents for detecting PDNLP, making it possible to diagnose any areas of detachment, including microdetachment of placenta, associated with inflammation.EFFECT: method is objective and reliable, improves quality of histological conclusion, high-informative and easy in assessment of results.1 cl, 4 ex
申请公布号 RU2601625(C1) 申请公布日期 2016.11.10
申请号 RU20150113491 申请日期 2015.04.14
申请人 Federalnoe gosudarstvennoe bjudzhetnoe uchrezhdenie "Ivanovskij nauchno-issledovatelskij institut materinstva i detstva imeni V.N. Gorodkova" Ministerstva zdravookhranenija Rossijskoj Federatsii 发明人 Peretjatko Ljubov Petrovna;Storozhenko Tatjana Vladimirovna;Fedulova JUlija Gennadevna
分类号 G01N33/53 主分类号 G01N33/53
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