发明名称 NOVEL PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR NEUROGENIC PAIN
摘要 The present invention relates to an agent for preventing and/or treating neuropathic pain comprising a 2-[(substituted-inden-7-yloxy)methyl]morpholine of the formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient. The invention is useful for providing an excellent agent for preventing and/or treating neuropathic pain, and particularly useful for providing an agent for preventing and/or treating allodynia, hyperalgesia, hyperesthesia, spontaneous pain, cancer pain, trigeminal neuralgia, phantom Limb pain, postherpetic neuralgia, fibromyalgia, low back/leg pain, thalamic pain, entrapment (compressive) peripheral neuropathy, atypical facial pain, pain accompanying spinal cord injury, pain accompanying multiple sclerosis, pain accompanying chemotherapy-induced neuropathy, cancer pain on which an analgesic effect of a narcotic analgesic such as morphine is insufficient, pain accompanying diabetic neuropathy, and the like.
申请公布号 EP2123642(A1) 申请公布日期 2009.11.25
申请号 EP20080722105 申请日期 2008.03.14
申请人 ASTELLAS PHARMA INC. 发明人 AOKI, TOSHIAKI;TAMURA, SEIJI
分类号 C07D265/30;A61K31/5375;A61P25/00 主分类号 C07D265/30
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