发明名称 |
Oncoprotein protein kinase |
摘要 |
An isolated polypeptide (JNK) characterized by having a molecular weight of 46 kD as determined by reducing SDS-PAGE, having serine and Threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of deterction of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
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申请公布号 |
US2005170381(A1) |
申请公布日期 |
2005.08.04 |
申请号 |
US20040972052 |
申请日期 |
2004.10.21 |
申请人 |
UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL |
发明人 |
KARIN MICHAEL;HIBI MASAHIKO;LIN ANNING |
分类号 |
A61K38/00;C07K16/40;C12N9/12;C12N15/54;(IPC1-7):C12Q1/68;G01N33/574 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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