| 摘要 |
<p>1-Benzyl-4-[(5,6-dimethoxy-1-indanon)-2-ylidene]methylpiperidine or a solvate thereof is catalytically hydrogenated in the presence of a palladium-alumina catalyst. According to need, the resultant reaction product is converted to a hydrochloride. Thus, 1-benzyl-4-[(5,6-dimethoxy-1indanon)-2-yl]methylpiperidine or a hydrochloride thereof, which are useful as a medicine, can be produced as a high-purity compound by a safer and easy operation suitable for industrial production.</p> |
