| 发明名称 | Ultrasonic catheter power control | ||
| 摘要 | A method of treating an occlusion at a treatment site within a patient's vasculature comprises providing an ultrasonic catheter. The ultrasonic catheter has a distal region, a proximal region opposite the distal region, a fluid delivery lumen having at least one opening in the distal region, and an ultrasound radiating member positioned within the distal region. The method further comprises positioning the ultrasonic catheter at the treatment site, such that at least a portion of the distal region is within the occlusion. The ultrasonic catheter further comprises passing a therapeutic compound through the fluid delivery lumen such that the therapeutic compound is delivered to the treatment site. The ultrasonic catheter further comprises emitting ultrasonic energy from the ultrasound radiating member. The emitted ultrasonic energy has an amplitude that is periodically varied between a low amplitude and a high amplitude. | ||
| 申请公布号 | US8852166(B1) | 申请公布日期 | 2014.10.07 |
| 申请号 | US201213528735 | 申请日期 | 2012.06.20 |
| 申请人 | Ekos Corporation | 发明人 | Keilman George;Hansmann Douglas R.;Soltani Azita;Wilson Richard R. |
| 分类号 | A61M31/00 | 主分类号 | A61M31/00 |
| 代理机构 | Knobbe Martens Olson & Bear, LLP | 代理人 | Knobbe Martens Olson & Bear, LLP |
| 主权项 | 1. A method of treating an occlusion at a treatment site within a patient's vasculature comprising: providing an ultrasonic catheter having a distal region, a proximal region opposite the distal region, a fluid delivery lumen having at least one opening in the distal region, and an ultrasound radiating member positioned within the distal region; positioning the ultrasonic catheter at the treatment site, such that at least a portion of the distal region is within the occlusion; passing a therapeutic compound through the fluid delivery lumen such that the therapeutic compound is delivered to the treatment site; and emitting ultrasonic energy from the ultrasound radiating member, wherein the emitted ultrasonic energy has an amplitude that is periodically varied between a low amplitude and a high amplitude,a high amplitude pulse duration of between approximately 1 millisecond and approximately 50 milliseconds, anda high amplitude pulse repetition rate of between approximately 5 hertz and approximately 150 hertz, andan in situ intensity at an energy radiating surface of between approximately 20 watts in−2 and approximately 90 watts in−2. | ||
| 地址 | Bothell WA US | ||