| 摘要 |
This invention relates generally to bifunctional molecules including (a) a TGF&bgr;RII or fragment thereof capable of binding TGF&bgr; and (b) an antibody, or antigen binding fragment thereof, that binds to an immune checkpoint protein, such as Programmed Death Ligand 1 (PD-L1), uses of such molecules (e.g., for treating cancer), and methods of making such molecules. |
