The present invention relates to the use of a live mutant Leishmania in the preparation of a vaccine and to vaccine formulations for use in immunising mammals, such as dogs and/or humans. The mutant Leishmania comprises at least one defective cysteine proteinase gene.
申请公布号
WO9844943(A1)
申请公布日期
1998.10.15
申请号
WO1998GB00994
申请日期
1998.04.03
申请人
THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW;MOTTRAM, JEREMY, CHARLES;COOMBS, GRAHAM, HERBERT