发明名称 |
DIRECTED DIFFERENTIATION AND MATURATION OF STEM CELL-DERIVED CARDIOMYOCYTES |
摘要 |
This invention provides an isolated electrophysiologically immature cell or its derivative that has been modified to provide a mature electrophysiological phenotype and populations of these cells. Compositions containing these cells and populations of cells are also provided by this invention. These cells and compositions have therapeutic and diagnostic uses. Non-limiting therapeutic uses include regenerating cardiac tissue, improving cardiac function, restoring action potential of cardiac tissue; and treating or preventing cardiac malfunction. The cells and population of cells also can be used diagnostically to screen drug or other therapeutic candidate. |
申请公布号 |
WO2008040027(A9) |
申请公布日期 |
2008.07.17 |
申请号 |
WO2007US80013 |
申请日期 |
2007.09.28 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;LI, RONALD;SIU, DAVID CW |
发明人 |
LI, RONALD;SIU, DAVID CW |
分类号 |
C12N5/00;C12N5/077;C12N15/00 |
主分类号 |
C12N5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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