| 发明名称 |
IMPROVED ADENOVIRUS FORMULATIONS |
| 摘要 |
This disclosure provides pharmaceutical adenovirus formulations, in particular, liquid pharmaceutical formulations comprising adenoviruses. |
| 申请公布号 |
US2016199426(A1) |
申请公布日期 |
2016.07.14 |
| 申请号 |
US201414916539 |
申请日期 |
2014.09.16 |
| 申请人 |
CRUCELL HOLLAND B.V. |
发明人 |
Adriaansen Janik |
| 分类号 |
A61K35/761;A61K47/10;A61K9/00;A61K47/26;A61K9/08;C12N7/00;A61K47/02;A61K47/12 |
主分类号 |
A61K35/761 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A formulation for adenoviruses, the formulation comprising:
a) a recombinant adenovirus; b) a citrate buffer; c) hydroxypropyl-beta-cyclodextrin (HBCD); d) a salt; and e) a non-ionic detergent;wherein said formulation has a pH of between 5.5 and 6.5. |
| 地址 |
Leiden NL |
