发明名称 HETEROARYL AMINE DERIVATIVE USEFUL AS PROTEIN KINASE INHIBITOR
摘要 The present invention relates to a heteroaryl amine compound having protein kinase inhibitory activity, a pharmaceutically acceptable salt thereof, and a pharmaceutical composition, containing the compound as an active ingredient, for preventing or treating diseases caused by abnormal cell growth. The novel compound of the present invention exhibits an excellent inhibitory effect on FGFR, which is a main inducer of bladder cancer or endometrial cancer, and a point mutation thereof, and various protein kinases involved in signaling, besides FGFR, and thus is useful as an agent for preventing and treating abnormal cell growth diseases caused by the protein kinases.
申请公布号 WO2016085221(A3) 申请公布日期 2016.09.15
申请号 WO2015KR12610 申请日期 2015.11.24
申请人 KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 发明人 SIM, Tae Bo;YOON, Ho Jong;YOON, Ji Hye;HUR, Woo Young;ROH, Eun Joo;KWAK, Yeon Ui
分类号 C07D403/14;A61K31/497;A61P35/00 主分类号 C07D403/14
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