发明名称 Thiazole compounds as protein kinase B (PKB) Inhibitors
摘要 The invention relates to methods of using thiazole compounds of Formula I and Formula II and compositions thereof for treating diseases mediated by protein kinase B (PKB) such as cancer and other proliferative disorders where the variables have the definitions provided herein.
申请公布号 ZA200806386(B) 申请公布日期 2009.11.25
申请号 ZA20080006386 申请日期 2008.07.23
申请人 AMGEN INC. 发明人 ZENG, QINGPING;ALLEN, JOHN G.;BOURBEAU, MATTHEW P.;DOMINGUEZ, CELIA;FOTSCH, CHRISTOPHER H.;HAH, NIANHE;HONG, FANG-TSAO;HUANG, XIN;LEE, MATTHEW R.;LI, AIWEN;LIU, QINGYIAN;RIDER, JAMES T.;TADESSE, SEIFU;TASKER, ANDREW S.;VISWANADHAN, VELLARKAD N.;WANG, XIANGHONG;WEILER, KURT E.;WOHLHIETER, GEORGE E.;YAO, GUOMIN;YUAN, CHESTER CHENGUANG
分类号 A61K;A61P;C07D 主分类号 A61K
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