| 摘要 |
Abstract Therapeutic compositions and/or formulations are provided, comprising: at least one cross linked protein matrix, wherein the, at least one cross-linked protein matrix comprises at least 5 one protein residue and at least one saccharide-containing residue, and methods of producing the same. The cross-linked protein matrix may be derived from cross-linking a full length or substantially full length protein, such as tropoelastin, elastin, albumin, collagen, collagen monomers, immunoglobulins, insulin, and/or derivatives or combinations thereof, with a saccharine containing cross-linking agent, such as a polysaccharide cross-linking agent derived 10 from, for example, hyaluronic acid or a cellulose derivative. The therapeutic compositions may be administered topically or by injection. The present disclosure also provides methods, systems, and/or kits for the preparation and/or formulation of the compositions disclosed herein. W:/NRPortbl/GHMatters/MICHELES/83912361 .docx 9/11/16 Io C) 0 o 0 0)0 a 0 Ht 0 < ' (0 (D |
