| 发明名称 |
ENHANCEMENT OF THE IMMUNE RESPONSE |
| 摘要 |
The technology described herein relates to compositions and methods for enhancing the immune response and/or reducing T cell tolerance in a subject. In some embodiments, the technology described herein relates to administering inhibitors of two or more of CEACAM1, PD1, and/or LAP to, e.g., synergistically reduce T cell tolerance. |
| 申请公布号 |
EP2906241(A4) |
申请公布日期 |
2016.06.08 |
| 申请号 |
EP20130845573 |
申请日期 |
2013.10.11 |
| 申请人 |
THE BRIGHAM AND WOMEN'S HOSPITAL, INC. |
发明人 |
BLUMBERG, RICHARD S.;HUANG, YU-HWA |
| 分类号 |
A61K39/395;A61K31/7088;A61P31/12;A61P35/00;A61P37/00 |
主分类号 |
A61K39/395 |
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