| 发明名称 |
TSPAN 33 IS A CANDIDATE FOR ANTIBODY TARGETED THERAPY FOR THE TREATMENT OF B CELL HODGKIN LYMPHOMAS |
| 摘要 |
A method of treating a disease associated with activated B lymphocytes expressing Tetraspanin 33 (TSPAN33/BAAM). The disease can be, for example, lymphoma or an immune disease. The method includes administering an anti-TSPAN33/BAAM antibody to a patient in need of such treatment in an amount effective to treat the disease. Methods of purifying activated B cells and identifying activated and/or diseased B cells are also provided. |
| 申请公布号 |
US2016237152(A1) |
申请公布日期 |
2016.08.18 |
| 申请号 |
US201314653572 |
申请日期 |
2013.12.20 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ;Universidad Autonoma De Nuevo León |
发明人 |
ZLOTNIK Albert;HEVEZI Peter;LUU Van;FLORES Juan Pablo |
| 分类号 |
C07K16/28;G01N33/569;C12Q1/68;C07K16/30 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating a lymphoma or leukemia in which TSPAN33 is upregulated, comprising administering an anti-TSPAN33 antibody to a patient in need of such treatment in an amount effective to treat the lymphoma or leukemia. |
| 地址 |
Oakland CA US |
