| 发明名称 |
Synthetic Route to 2'-Deoxy-2',2'-Difluorotetrahydrouridines |
| 摘要 |
The present invention relates to methods and intermediates for synthesizing 2′-deoxy-2′,2′-difluorotetrahydrouridine compounds. |
| 申请公布号 |
US2016237107(A1) |
申请公布日期 |
2016.08.18 |
| 申请号 |
US201415027022 |
申请日期 |
2014.10.29 |
| 申请人 |
CHOI Hyeong-Wook;Mathieu Steven;Fang Frank Matthew;Lewis Bryan Matthew;Otsuka Pharmaceutical Co., Ltd. |
发明人 |
Choi Hyeong-wook;Mathieu Steven;Fang Frank;Lewis Bryan Matthew |
| 分类号 |
C07H19/06;C07H1/06;C07H1/00;C07B57/00 |
主分类号 |
C07H19/06 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of producing compound 1: or a salt thereof; comprising precipitating or crystallizing compound 1 from a solution of compound 2: in the presence of a catalyst. |
| 地址 |
Andover MA US |
