摘要 |
The present invention relates to piperazine derivatives of formulae Ia, Ib, Ic and Id and their use to treat multiple myeloma. where R<SUP>1a</SUP>, R<SUP>1b</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>6</SUP>, R<SUP>9</SUP>, R<SUP>10 </SUP>and Y are as defined herein. |