发明名称 Compuesto n-((4as,6ar,6bs,8ar,12as,14ar,14bs)-11-ciano-2,2,6a,6b,9,9,12a-heptametil-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahidropicen-4a-il)-2,2-difluoropropanamida; forma polimorfica; composicion farmaceutica; y uso para tratar o prevenir la inflamacion y el estres oxidativo, entre otras enfermedades.
摘要 The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.
申请公布号 CL2014002886(A1) 申请公布日期 2015.02.06
申请号 CL20140002886 申请日期 2014.10.24
申请人 REATA PHARMACEUTICALS INC 发明人 ANDERSON ERIC;LIU XIAOFENG;DECKER ANDREA
分类号 C07J63/00;A61K31/565;A61P1/04;A61P1/16;A61P1/18;A61P3/10;A61P11/00;A61P11/06;A61P17/00;A61P17/02;A61P17/06;A61P17/10;A61P17/14;A61P19/02;A61P27/02;A61P27/06;A61P29/00;A61P31/02;A61P35/00;A61P35/02;A61P37/00;A61P37/06 主分类号 C07J63/00
代理机构 代理人
主权项
地址