发明名称 |
Compuesto n-((4as,6ar,6bs,8ar,12as,14ar,14bs)-11-ciano-2,2,6a,6b,9,9,12a-heptametil-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahidropicen-4a-il)-2,2-difluoropropanamida; forma polimorfica; composicion farmaceutica; y uso para tratar o prevenir la inflamacion y el estres oxidativo, entre otras enfermedades. |
摘要 |
The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof. |
申请公布号 |
CL2014002886(A1) |
申请公布日期 |
2015.02.06 |
申请号 |
CL20140002886 |
申请日期 |
2014.10.24 |
申请人 |
REATA PHARMACEUTICALS INC |
发明人 |
ANDERSON ERIC;LIU XIAOFENG;DECKER ANDREA |
分类号 |
C07J63/00;A61K31/565;A61P1/04;A61P1/16;A61P1/18;A61P3/10;A61P11/00;A61P11/06;A61P17/00;A61P17/02;A61P17/06;A61P17/10;A61P17/14;A61P19/02;A61P27/02;A61P27/06;A61P29/00;A61P31/02;A61P35/00;A61P35/02;A61P37/00;A61P37/06 |
主分类号 |
C07J63/00 |
代理机构 |
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代理人 |
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