An earphone and a media player system are provided. The earphone may include: a first sensor unit and a second sensor unit respectively mounted on a left portion and a right portion of the earphone, adapted to sensing gestures and generating signals according to the sensed gestures, where the left portion and the right portion are disposed on two sides of a user's head when the user wears the earphone; a processing device, adapted to translating the signals into control instructions to control a media player; and an interface, adapted to transmitting the control instructions to the media player. Unintended operations may be reduced.