PATIENT-SPECIFIC TEMPORARY IMPLANTS FOR ACCURATELY GUIDING LOCAL MEANS OF TUMOR CONTROL ALONG PATIENT-SPECIFIC INTERNAL CHANNELS TO TREAT CANCER

摘要

The present invention offers an alternative for cancer treatment where radiation, thermotherapy, or another therapeutic modality must be delivered to an internal cavity of a subject, for example to treat mouth, anal, cervical, and vaginal cancers. The invention is a new approach that builds on recent results in 3D printing and steerable needle motion planning to create customized implants containing customized curvature-constrained internal channels that fit securely, minimize air gaps, and precisely guide treatment sources through internal printed channels to accurately reach tumors and minimize damage to healthy tissue.

主权项

1. A removably implantable device customized to be positioned proximal to an internal surface of a body cavity of a subject in which said device is implanted, said device configured to provide localization of at least one local means of tumor control to a diseased tissue of said subject proximate to said body cavity, said device comprising:
(a) a device body comprising an exterior surface configured to contact said internal surface of said body cavity, and an internal region having at least one curvature constrained channel disposed therein, said at least one curvature constrained channel being configured to accept said at least one local means of tumor control, and comprising at least one opening communicating with said external surface.