Method for producing N-(3-ethynyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine (erlotinib) from 6,7-bis(2-methoxyethoxy)quinazolin-4(3H)-one and 3-ethynylaniline in presence of titanium(IV) chloride and anisole.
申请公布号
LV14953(A)
申请公布日期
2015.02.20
申请号
LV20130000116
申请日期
2013.08.14
申请人
LATVIJAS ORGANISK&Amacr,S SINT&Emacr,ZES INSTIT&Umacr,TS