发明名称 COMPOSITIONS COMPRISING THE NC2 DOMAIN OF COLLAGEN IX AND METHODS OF USING SAME
摘要 The present invention relates to the newly identified timerization initiating and stagger determining capacity of the NC2 domain of collagen IX. The invention further relates to a hexavalent molecular building block wherein the linkage of additional moieties to the amino and carboxyl terminals of monomers comprising the NC2 domain of collagen IX promotes the directed association of those moieties via the trimerization initiating and stagger determining capacity of the NC2 domain of collagen IX.
申请公布号 US2016222089(A1) 申请公布日期 2016.08.04
申请号 US201615132453 申请日期 2016.04.19
申请人 SHRINERS HOSPITAL FOR CHILDREN 发明人 Bachinger Hans Peter;Budko Sergey P.
分类号 C07K14/78;G01N33/68;A61K47/48 主分类号 C07K14/78
代理机构 代理人
主权项 1. A composition comprising a heterologous moiety operably linked to a NC2 domain composition.
地址 Tampa FL US