METHODS FOR PRODUCING METALATED ORGANIC COMPOUNDS

摘要

The present invention relates to methods for producing metalated organic compounds R1-Met under continuous flow conditions. The invention further relates to the metalated compounds obtained by these methods, and to the further reaction thereof with electrophilic reagents and the compounds obtained thereby. The invention also relates to methods for producing metalated organic compounds with Lewis-acidic hydrogen R1-Met using the base Cy2NLi.