发明名称 |
USE OF PEPTIDE-BASED INHIBITORS OF THE STAT3-IL10 PATHWAY FOR TREATING BACTERIAL INFECTION AND GRANULOMATOUS DISEASE |
摘要 |
The invention provides a method of treating pathogenic bacterial infection (e.g., tuberculosis infection) in an animal comprising administering a peptide-based inhibitor of the STAT3-IL10 pathway or a nucleic acid encoding the peptide-based inhibitor to the animal. The invention also provides methods of treating chronic granulomatous disease and Wegener's granulomatosis in an animal comprising administering a peptide-based inhibitor of the STAT3-IL10 pathway or a nucleic acid encoding the peptide-based inhibitor to the animal. |
申请公布号 |
WO2016112193(A1) |
申请公布日期 |
2016.07.14 |
申请号 |
WO2016US12493 |
申请日期 |
2016.01.07 |
申请人 |
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;COLORADO STATE UNIVERSITY RESEARCH FOUNDATION |
发明人 |
TARASOVA, NADYA I.;GONZALEZ-JUARRERO, MERCEDES |
分类号 |
A61K38/17;A61K38/20;A61K45/06;A61P11/00;A61P31/06;C07K14/00 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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